000 03061cam a2200373 i 4500
001 1187220557
003 OCoLC
005 20210330104541.0
008 200929s2021 nyua b 001 0deng
010 _a2020043552
020 _a9781982115852
040 _aDLC
_beng
_erda
_cDLC
050 0 0 _aQH440
_b.I83 2021
082 0 0 _a576.5
_223
100 1 _aIsaacson, Walter,
_eauthor.
_96489
245 1 4 _aThe code breaker :
_bJennifer Doudna, gene editing, and the future of the human race /
_cWalter Isaacson.
246 3 _aJennifer Doudna, gene editing, and the future of the human race.
250 _aFirst Simon & Schuster hardcover edition.
264 1 _aNew York :
_bSimon & Schuster,
_c2021.
264 4 _c ©2021.
300 _axix, 536 pages :
_billustrations (chiefly color) ;
_c25 cm.
336 _atext
_btxt
_2rdacontent.
336 _astill image
_2rdacontent.
337 _aunmediated
_bn
_2rdamedia.
338 _avolume
_bnc
_2rdacarrier.
504 _aIncludes bibliographical references (pages 487-516) and index.
505 0 _aIntroduction. Into the breach -- Part one. The origins of life. Hilo ; The gene ; DNA ; The education of a biochemist ; The human genome ; RNA ; Twists and folds ; Berkeley -- Part two. CRISPR. Clustered repeats ; The Free Speech Movement Café ; Jumping in ; The yogurt makers ; Genentech ; The lab ; Caribou ; Emmanuelle Charpentier ; CRISPR-Cas9 ; Science, 2012 ; Dueling presentations -- Part three. Gene editing. A human tool ; The race ; Feng Zhang ; George Church ; Zhang tackles CRISPR ; Doudna joins the race ; Photo finish ; Doudna's final sprint ; Forming companies ; Mon amie ; The heroes of CRISPR ; Patents -- Part four. CRISPR in action. Therapies ; Biohacking ; DARPA and anti-CRISPR -- Part five. Public scientist. Rules of the road ; Doudna steps in -- Part six. CRISPR babies. He Jiankui ; The Hong Kong summit ; Acceptance -- Part seven. Moral questions. Red lines ; Thought experiments ; Who should decide? ; Doudna's ethical journey -- Part eight. Dispatches from the front. Quebec ; I learn to edit ; Watson revisited ; Doudna pays a visit -- Part nine. Coronavirus. Call to arms ; Testing ; The Berkeley lab ; Mammoth and Sherlock ; Coronavirus tests ; Vaccines ; CRISPR cures ; Cold Spring Harbor virtual ; The Nobel Prize.
520 _aDriven by a passion to understand how nature works and to turn discoveries into inventions, Doudna and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. Isaacson explores the development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. -- Adapted from jacket.
600 1 0 _aDoudna, Jennifer A.
_96490
650 0 _aCRISPR (Genetics)
_96491
650 0 _aGene editing.
_96492
856 4 2 _zCornerstones of Science website
_uhttp://www.cornerstonesofscience.org/
942 _2ddc
_cBOOK
999 _c27416
_d27416